Center for the Study of Movement, Cognition, and Mobility
R&D > Laboratories > Center for the Study of Movement, Cognition, and Mobility – Prof. Jeff Hausdorff
Our Vision
As the baby boomers age, the number of adults who suffer from frequent falls, gait disorders, cognitive impairment, dementia, and other neurological diseases continues to increase dramatically. New understandings and therapeutic approaches are needed. Our research aims to improve the personalized treatment of age-related movement, cognition, and mobility disorders and to alleviate the burden associated with them.
We leverage a combination of clinical, engineering, and neuroscience expertise:
• To gain new understandings into the physiologic and pathophysiologic mechanisms that contribute to cognitive and motor function, the factors that influence these functions, and their changes with aging and disease (e.g., Parkinson’s disease, Alzheimer’s).
• To develop new methods and tools for the early detection and tracking of cognitive and motor decline.
• To develop and evaluate novel methods for the prevention and treatment of gait, falls, and cognitive function.
Contact Us
Primary Investigators
Prof. Jeff Hausdorff, Director
Department of Physical, Sackler Faculty of Medicine, TAU; Sagol School of Neuroscience, TAU
Phone: +972-3-6973081
Email: jhausdor@tlvmc.gov.il
Prof. Anat Mirelman, Associate Director
Phone: +972-3-6947513
Email: anatmi@tlvmc.gov.il
Meital Zahavi Schreiber, Lab Manager
Phone: +972-3-6947513
Email: meitalzs@tlvmc.gov.il
Address
Rehabilitation building
Floor minus 1 13 Henrietta Szold Street, Tel Aviv
Research
This multi-center study is being conducted with the input of 34 centers is designed to connect digital mobility assessment to clinical outcomes for regulatory and clinical endorsement. Technical and clinical validation is being performed in five clinical cohorts (e.g., Parkinson’s disease, multiple sclerosis, post-hip fracture).
In conjunction with researchers at Rush University, this work examines the relationships between AD pathologies and related disorders in brain, brainstem, and spinal cord to gait.
In collaboration with researchers at Columbia University, this research aims to generate new insights into the neural basis of the most important and central features of cognitive aging and its association with changes in gait and mobility
The goal of this work is to evaluate the effects of intelligent, Smartphone-based cueing on freezing of gait in patients with Parkinson’s disease.
This research aims to assess the feasibility of providing tele-rehabilitation over an extended period to people with Parkinson’s disease using wearable devices and a dedicated Smartphone app
Working with Owlytics Healthcare, we are developing new markers of motor function and health status based on data collected from a SmartWatch in people with multiple sclerosis.
In collaboration with researchers at Columbia University, we are developing measures of physical activity, gait and chorea from a wrist-worn sensor in people with Huntington’s disease.
This work aims to evaluate the potential of using non-invasive brain stimulation to improve gait and cognitive function among people with Parkinson’s disease.
Gallery
Our Team
Current Staff
Researchers
- Jeff Hausdorff
- Anat Mirelman
- Inbal Maidan
- Talia Herman
- Eran Gazit
- Marina Brozgol
- Pablo Cornejo Thumm
- David Buzaglo
- Keren Cochavi
- Nimrod Geffen
- Shahar Yehezkyahu
- Amit Salomon
Students
- Ira Galperin
- Dafna Schwartz
- Assaf Zadka
- Miriam Urbach
- Maya Thatcher
- Galia Shaham
- Yonatan Brand
- Shlomit Haim
- Or Engelhardt
Past Staff
- Tal Reches
- Aner Weiss
- Natalie Ganz
- Ayala Saban
- Leor Gruendlinger
- Inbar Hillel
- Shirley Shema
- Moran Dorman
- Mor Frank
- Ilan Kurz
- Hagar Brandt
- Tal Freedman
- Shiran Shustak
- Ariel Tankus
- Meir Plotnik
- Yoav Beck;
- Keren Rosenberg-Katz
- Yael Jacob
Current funding
Highlighted Publications
Keren K, Busse M, Fritz NE, Muratori LM, Gazit E, Hillel I, Scheinowitz M, Gurevich T, Inbar N, Omer N, Hausdorff JM, Quinn L
Front Neurol. 2021;12:719442
Impaired Inhibitory Control During Walking in Parkinson’s Disease Patients: An EEG Study.
Sosnik R, Danziger-Schragenheim S, Possti D, Fahoum F, Giladi N, Hausdorff JM, Mirelman A, Maidan I
J Parkinsons Dis. 2021
Multitarget Transcranial Electrical Stimulation for Freezing of Gait: A Randomized Controlled Trial.
Manor B, Dagan M, Herman T, Gouskova NA, Vanderhorst VG, Giladi N, Travison TG, Pascual-Leone A, Lipsitz LA, Hausdorff JM.
Mov Disord. 2021;36:2693-2698.
More Publications >>
A multimodal approach using TMS and EEG reveals neurophysiological changes in Parkinson’s disease.
Maidan I, Zifman N, Hausdorff JM, Giladi N, Levy-Lamdan O, Mirelman A.
Parkinsonism Relat Disord. 2021;89:28-33.
Targeted tDCS Mitigates Dual-Task Costs to Gait and Balance in Older Adults.
Zhou J, Manor B, Yu W, Lo OY, Gouskova N, Salvador R, Katz R, Cornejo TP, Brozgol M, Ruffini G, Pascual-Leone A, Lipsitz LA, Hausdorff JM.
Ann Neurol. 2021;90:428-439.
Detecting Sensitive Mobility Features for Parkinson’s Disease Stages Via Machine Learning.
Mirelman A, Ben Or FM, Melamed M, Granovsky L, Nieuwboer A, Rochester L, Del DS, Avanzino L, Pelosin E, Bloem BR, Della CU, Cereatti A, Bonato P, Camicioli R, Ellis T, Hamilton JL, Hass CJ, Almeida QJ, Inbal M, Thaler A, Shirvan J, Cedarbaum JM, Giladi N, Hausdorff JM.
Mov Disord. 2021;36:2144-2155.
Maidan I, Mirelman A, Hausdorff JM, Stern Y, Habeck CG
Sci Rep. 2021;11:6600.
Schneider N, Dagan M, Katz R, Thumm PC, Brozgol M, Giladi N, Manor B, Mirelman A, Hausdorff JM.
J Neuroeng Rehabil. 2021;18:23.
Del DS, Kirk C, Yarnall AJ, Rochester L, Hausdorff JM.
J Parkinsons Dis. 2021;11:S35-S47.
Wayne PM, Gow BJ, Hou F, Ma Y, Hausdorff JM, Lo J, Rist PM, Peng CK, Lipsitz LA, Novak V, Manor B.
PLoS One 2021. ;16:e0242963.
Galperin I, Herman T, Assad M, Ganz N, Mirelman A, Giladi N, Hausdorff JM.
Sensors (Basel). 2020 ;20.
Vascular health across young adulthood and midlife cerebral autoregulation, gait, and cognition.
Mahinrad S, Shownkeen M, Sedaghat S, Yaffe K, Hausdorff JM, Lloyd-Jones DM, Gorelick PB, Sorond FA
Alzheimers Dement. 2021;17:745-754.
Ganz N, Gazit E, Giladi N, Dawe RJ, Mirelman A, Buchman AS, Hausdorff JMJ Gerontol A Biol Sci Med Sci. 2021;76:101-107.
Dagan M, Herman T, Bernad-Elazari H, Gazit E, Maidan I, Giladi N, Mirelman A, Manor B, Hausdorff JM.
J Neurol. 2021;268:658-668.
Possti D, Fahoum F, Sosnik R, Giladi N, Hausdorff JM, Mirelman A, Maidan I.
J Neurol. 2021;268:161-168.
Droby A, El Mendili MM, Giladi N, Hausdorff JM, Maidan I, Mirelman A.
Gait Posture. 2021;90:99-105.
